Journal of Innovative Optical Health Sciences, Volume. 14, Issue 5, 2142006(2021)

Glycerol effects on optical, weight and geometrical properties of skin tissue

Vadim D. Genin1,2, Elina A. Genina1,2、*, Valery V. Tuchin1,2,3, and Alexey N. Bashkatov1,2
Author Affiliations
  • 1Saratov State University (National Research University) 83, Astrakhanskaya Str., Saratov 410012, Russia
  • 2Tomsk State University (National Research University) 36, Lenina Av., Tomsk 634050, Russia
  • 3Institute of Precise Mechanics and Control of RAS 24, Rabochaya Str., Saratov 410028, Russia
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    References(52)

    [1] [1] E. A. Genina, A. N. Bashkatov, Yu. P. Sinichkin, I. Yu. Yanina, V. V. Tuchin, Optical Clearing of Tissues: Benefits for Biology, Medical Diagnostics and Phototherapy, Handbook on Optical Biomedical Diagnostics, Vol. 2: Methods, Chap. 10, 2nd Edition, V. V. Tuchin, Ed., pp. 565–937, SPIE Press, Bellingham, Washington (2016).

    [2] [2] E. A. Genina, L. M. C. Oliveira, A. N. Bashkatov, V. V. Tuchin, Optical Clearing of Biological Tissues: Prospects of Application for Multimodal Malignancy Diagnostics, Multimodal Optical Diagnostics of Cancer, Chap. 3, V. V. Tuchin, J. Popp, V. Zakharov, Eds., pp. 107–132, Springer Nature, Cham (2020).

    [3] [3] R. Christoph, B. Schmidt, U. Steinberner, W. Dilla, R. Karinen, Glycerol, in Ullmann's Encyclopedia of Industrial Chemistry, Vol. 17, pp. 77–81, Wiley- VCH Verlag GmbH & Co. KGaA, Weinheim (2012).

    [4] [4] J. Jiang, M. Boese, P. Turner, R. K. Wang, "Penetration kinetics of dimethyl sulphoxide and glycerol in dynamic optical clearing of porcine skin tissue in vitro studied by Fourier transform infrared spectroscopic imaging," J. Biomed. Opt. 13, 021105 (2008).

    [5] [5] E. A. Genina, A. N. Bashkatov, V. V. Tuchin, "Optical clearing of cranial bone," Adv. Opt. Technol. 2008, 267867 (2008).

    [6] [6] M. A. Fox, D. G. Diven, K. Sra, A. Boretsky, T. Poonawalla, A. Readinger, M. Motamedi, R. J. McNichols, "Dermal scatter reduction in human skin: A method using controlled application of glycerol," Lasers Surg. Med. 41, 251–255 (2009).

    [7] [7] X. Wen, Z. Mao, Z. Han, V. V. Tuchin, D. Zhu, "In vivo skin optical clearing by glycerol solutions: Mechanism," J. Biophoton. 3, 44–52 (2010).

    [8] [8] H. Zhong, Z. Guo, H. Wei, C. Zeng, H. Xiong, Y. He, S. Liu, "In vitro study of ultrasound and differentconcentration glycerol-induced changes in human skin optical attenuation assessed with optical coherence tomography," J. Biomed. Opt. 15, 036012 (2010).

    [9] [9] H. Q. Zhong, Z. Y. Guo, H. J. Wei, C. C. Zeng, H. L. Xiong, Y. H. He, S. H. Liu, "Quantification of glycerol diffusion in human normal and cancer breast tissues in vitro with optical coherence tomography," Laser Phys. Lett. 7, 315–320 (2010).

    [10] [10] E. A. Genina, A. N. Bashkatov, Yu. P. Sinichkin, V. V. Tuchin, "Optical clearing of skin under action of glycerol: Ex vivo and in vivo investigations," Opt. Spectrosc. 109, 225–231 (2010).

    [11] [11] T. Yu, X. Wen, V. V. Tuchin, Q. Luo, D. Zhu, "Quantitative analysis of dehydration in porcine skin for assessing mechanism of optical clearing," J. Biomed. Opt. 16, 095002 (2011).

    [12] [12] V. D. Genin, D. K. Tuchina, A. J. Sadeq, E. A. Genina, V. V. Tuchin, A. N. Bashkatov, "Ex vivo investigation of glycerol diffusion in skin tissue," J. Biomed. Photon. Eng. 2, 010303 (2016).

    [13] [13] T. Yu, Y. Qi, J. Wang, W. Feng, J. Xu, J. Zhu, Y. Yao, H. Gong, Q. Luo, D. Zhu, "Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol," J. Biomed. Opt. 21, 081203 (2016).

    [14] [14] D. K. Tuchina, A. N. Bashkatov, A. B. Bucharskaya, E. A. Genina, V. V. Tuchin, "Study of glycerol diffusion in skin and myocardium ex vivo under the conditions of developing alloxan-induced diabetes," J. Biomed. Photon. Eng. 3, 020302 (2017).

    [15] [15] E. A. Genina, A. N. Bashkatov, Yu. P. Sinichkin, I. Yu. Yanina, V. V. Tuchin, "Optical clearing of biological tissues: Prospects of application in medical diagnostics and phototherapy," J. Biomed. Photon. Eng. 1, 22–58 (2015).

    [16] [16] A. Yu. Sdobnov, M. E. Darvin, E. A. Genina, A. N. Bashkatov, J. Lademann, V. V. Tuchin, "Recent progress in tissue optical clearing for spectroscopic application," Spectrochim. Acta A: Mol. Biomol. Spectrosc. 197, 216–229 (2018).

    [17] [17] R. Cicchi, F. S. Pavone, D. Massi, D. D. Sampson, "Contrast and depth enhancement in two-photon microscopy of human skin ex vivo by use of optical clearing agents," Opt. Exp. 13, 2337–2344 (2005).

    [18] [18] D. Huang, W. Zhang, H. Zhong, H. Xiong, X. Guo, Z. Guo, "Optical clearing of porcine skin tissue in vitro studied by Raman microspectroscopy," J. Biomed. Opt. 17, 015004 (2012).

    [19] [19] R. K. Wang, X. Xu, V. V. Tuchin, J. B. Elder, "Concurrent enhancement of imaging depth and contrast for optical coherence tomography by hyperosmotic agents," JOSA B 18, 948–953 (2001).

    [20] [20] M. V. Schulmerich, K. A. Dooley, T. M. Vanasse, S. A. Goldstein, M. D. Morris, "Subsurface and transcutaneous Raman spectroscopy and mapping using concentric illumination rings and collection with a circular fiber optic array," Appl. Spectrosc. 61, 671–678 (2007).

    [21] [21] P. A. Timoshina, E. M. Zinchenko, D. K. Tuchina, M. M. Sagatova, O.V. Semyachkina-Glushkovskaya, V. Valery, "Laser speckle contrast imaging of cerebral blood flow of newborn mice at optical clearing," Proc. SPIE 10336, 1033610 (2017).

    [22] [22] E. Song, Y. Ahn, J. Ahn, S. Ahn, C. Kim, S. Choi, R. M. Boutilier, Y. Lee, P. Kim, H. Lee, "Optical clearing assisted confocal microscopy of ex vivo transgenic mouse skin," Opt. Laser Technol. 73, 63–76 (2015).

    [23] [23] I. Carneiro, S. Carvalho, R. Henrique, R. Oliveira, V. V. Tuchin, "Simple multimodal optical technique for evaluation of free/bound water and dispersion of human liver tissue," J. Biomed. Opt. 22, 125002 (2017).

    [24] [24] T. Son, B. Jung, "Cross-evaluation of optimal glycerol concentration to enhance optical clearing efficacy," Skin Res. Technol. 21, 327–332 (2015).

    [25] [25] J. Yoon, D. Park, T. Son, J. Seo, J. S. Nelson, B. Jung, "A physical method to enhance transdermal delivery of a tissue optical clearing agent: Combination of microneedling and sonophoresis," Lasers Surg. Med. 42, 412–417 (2010).

    [26] [26] I. Carneiro, S. Carvalho, R. Henrique, R. Oliveira, V. V. Tuchin, "Kinetics of optical properties of colorectal muscle during optical clearing," IEEE J. Sel. Top. Quantum. Electron. 25, 7200608 (2019).

    [27] [27] E. A. Genina, A. N. Bashkatov, A. A. Korobko, E. A. Zubkova, V. V. Tuchin, I. Yaroslavsky, G. B. Altshuler, "Optical clearing of human skin: Comparative study of permeability and dehydration of intact and photothermally perforated skin," J. Biomed. Opt. 13, 021102 (2008).

    [28] [28] V. Hovhannisyan, P.-S. Hu, S.-J. Chen, C.-S. Kim, C.-Y. Dong, "Elucidation of the mechanisms of optical clearing in collagen tissue with multiphoton imaging," J. Biomed. Opt. 18, 046004 (2013).

    [29] [29] Z. Mao, D. Zhu, Y. Hu, X. Wen, Z. Han, "Influence of alcohols on the optical clearing effect of skin in vitro," J. Biomed. Opt. 13, 021104 (2008).

    [30] [30] A. T. Yeh, B. Choi, J. S. Nelson, B. J. Tromberg, "Reversible dissociation of collagen in tissues," J. Invest. Dermatol. 121, 1332–1335 (2003).

    [31] [31] J. M. Hirshburg, K. M. Ravikumar, W. Hwang, A. T. Yeh, "Molecular basis for optical clearing of collagenous tissues," J. Biomed. Opt. 15, 055002 (2010).

    [32] [32] E. I. Galanzha, V. V. Tuchin, A. V. Solovieva, T. V. Stepanova, Q. Luo, H. Cheng, "Skin backreflectance and microvascular system functioning at the action of osmotic agents," J. Phys. D: Appl. Phys. 36, 1739–1746 (2003).

    [33] [33] G. Vargas, A. Readinger, S. S. Dosier, A. J. Welch, "Morphological changes in blood vessels produced by hyperosmotic agents and measured by optical coherence tomography," Photochem. Photobiol. 77, 541–549 (2003).

    [34] [34] D. Zhu, J. Zhang, H. Cui, Z. Mao, P. Li, Q. Luo, "Short-term and long-term effects of optical clearing agents on blood vessels in chick chorioallantoic membrane," J. Biomed. Opt. 13, 021106 (2008).

    [35] [35] A. N. Bashkatov, K. V. Berezin, K. N. Dvoretskiy, M. L. Chernavina, E. A. Genina, V. D. Genin, V. I. Kochubey, E. N. Lazareva, A. B. Pravdin, M. E. Shvachkina, P. A. Timoshina, D. K. Tuchina, D. D. Yakovlev, D. A. Yakovlev, I. Yu. Yanina, O. S. Zhernovaya, V. V. Tuchin, "Measurement of tissue optical properties in the context of tissue optical clearing," J. Biomed. Opt. 23, 091416 (2018).

    [36] [36] R. Samatham, K. G. Phillips, S. L. Jacques, "Assessment of optical clearing agents using reflectance- mode confocal scanning laser microscopy," J. Innov. Opt. Health Sci. 3, 183–188 (2010).

    [37] [37] P. Schiebener, J. Straub, J. M. H. LeveltSengers, J. S. Gallagher, "Refractive index of water and steam as function of wavelength, temperature and density," J. Phys. Chem. Ref. Data 19, 677–717 (1990).

    [38] [38] M. V. Noble, A. B. Garrett, "A thermodynamic study of lead chloride in dioxane-water by means of electromotive force and solubility data at 25; the acetone-, ethanol-, dioxane-, glycerol–water–lead chloride systems," J. Am. Chem. Soc. 66, 231–235 (1944).

    [39] [39] D. K. Tuchina, A. N. Bashkatov, E. A. Genina, V. V. Tuchin, "Investigation of the impact of immersion agents on weight and geometric parameters of myocardial tissue in vitro," Biophysics 63, 791– 797 (2018).

    [40] [40] V. V. Tuchin, Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis, SPIE Tutorial Text in Optical Engineering, 3rd Edition, SPIE Press, Washington, Bellingham (2015).

    [41] [41] M. L. Sheeley, "Glycerol viscosity tables," Ind. Eng. Chem. 24, 1060–1064 (1932).

    [42] [42] J. W. Wiechers, J. C. Dederen, A. V. Rawlings, "Moisturization mechanisms: Internal occlusion by orthorhombic lipid phase stabilizers — a novel mechanism of skin moisturization," Skin Moisturization, Chap. 19, A. V. Rawlings, J. J. Leyden, Eds., pp. 309–321, Taylor and Francis, London (2009).

    [43] [43] F. O. Akinkunmi, D. A. Jahn, N. Giovambattista, "Effects of temperature on the thermodynamic and dynamical properties of glycerol-water mixtures: A computer simulation study of three different force fields," J. Phys. Chem. B 119, 6250–6261 (2015).

    [44] [44] G. D'Errico, O. Ortona, F. Capuano, V. Vitagliano, "Diffusion coefficients for the binary system glyceroltwater at 25C. A velocity correlation study," J. Chem. Eng. Data 49, 1665–1670 (2004).

    [45] [45] N. Cheron, M. Naepels, E. Pluha?ova, D. Laage, "Protein preferential solvation in water: Glycerol mixtures," J. Phys. Chem. B 124, 1424–1437 (2020).

    [46] [46] K. V. Berezin, K. N. Dvoretskiy, M. L. Chernavina, A. M. Likhter, V. V. Smirnov, I. T. Shagautdinova, E. M. Antonova, E. Yu. Stepanovich, E. A. Dzhalmuhambetova, V. V. Tuchin, "Molecular modeling of immersion optical clearing of biological tissues," J. Mol. Model. 24, 45 (2018).

    [47] [47] E. Youn, T. Son, H.-S. Kim, B. Jung, "Determination of optimal glycerol concentration for optical tissue clearing," Proc. SPIE 8207, 82070J (2012).

    [48] [48] R. K. Wang, J. B. Elder, "Propylene glycol as a contrasting agent for optical coherence tomography to image gastrointestinal tissues," Lasers Surg. Med. 30, 201–208 (2002).

    [49] [49] X. Xu, Q. Zhu, "Sonophoretic delivery for contrast and depth improvement in skin optical coherence tomography," IEEE J. Sel. Top. Quant. Electron. 14, 56–61 (2008).

    [50] [50] J. Wang, Y. Liang, S. Zhang, Y. Zhou, H. Ni, Y. Li, "Evaluation of optical clearing with the combined liquid paraffin and glycerol mixture," Biomed. Opt. Exp. 2, 2329–2338 (2011).

    [51] [51] S. V. Zaitsev, Y. I. Svenskaya, E. V. Lengert, G. S. Terentyuk, A. N. Bashkatov, V. V. Tuchin, E. A. Genina, "Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles," J. Biophoton. 13, e201960020 (2020).

    [52] [52] S. Tran, S. Zaytsev, V. Charykova, M. Yusupova, A. Bashkatov, E. Genina, V. Tuchin, W. Blondel, M. Amouroux, "Analysis of image features for the characterization of skin optical clearing kinetics performed on in vivo and ex vivo human skin using Linefield-Confocal Optical Coherence Tomography (LC-OCT)," Proc. SPIE 11553, 115532P (2020).

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    Vadim D. Genin, Elina A. Genina, Valery V. Tuchin, Alexey N. Bashkatov. Glycerol effects on optical, weight and geometrical properties of skin tissue[J]. Journal of Innovative Optical Health Sciences, 2021, 14(5): 2142006

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    Paper Information

    Received: May. 31, 2021

    Accepted: Aug. 1, 2021

    Published Online: Dec. 6, 2021

    The Author Email: Elina A. Genina (eagenina@yandex.ru)

    DOI:10.1142/s1793545821420062

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