Chinese Journal of Lasers, Volume. 49, Issue 24, 2407205(2022)

Noninvasive Quantitative Assessment of Burn Degree Based on Spatial Frequency-Domain Imaging

Xiaoxue Zhong, Guowu Huang, Hongbo Miu, Chenghao Hu, Wei Liu, Chunrong Sun, Zhihua Chen, Gangning Li, Zili Cao, Xin Jin, and Weihao Lin*
Author Affiliations
  • College of Optometry (College of Biomedical Engineering), Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
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    Figures & Tables(11)
    Two-frequency MTF (DC versus AC) lookup table for rapid calculation of optical parameters (μa and μs')
    Portable quantitative burn imager. (a) Device physical map; (b) optical path schematic
    Time distribution of dorsal burns in SD rats
    Data processing flowchart and data visualization interface. (a) Data processing flowchart; (b) data visualization interface
    Pictures of rat burn skin. (a) Before burn (blank group); (b) 4 s group; (c) 12 s group; (d) 24 s group
    Variation of optical parameters of three groups of different burn areas with time under three wavelengths (the parameter value corresponding to each time period is the average value of ROI area, and its standard deviation is also given. Mann-Whitney U-test is used to compare the differences of data, and the level of significant difference is represented by“*”and * represents P<0.05).(a)-(c) Relative change of absorption coefficient of burn area to the area before burn at each time period under R, G, B wavelengths; (d)-(f) relative change of reduced scattering coefficient of burn area to the area before burn at each time period under R, G, B wavelengths
    Systematic clustering. (a) Systematic clustering flowchart; (b) aggregation coefficient line chart
    Systematic clustering results. (a) 10 min after burn; (b) 120 min after burn
    Factor boxplot at different burn stages. (a) 5 min after burn; (b) 10 min after burn; (c) 30 min after burn; (d) 60 min after burn; (e) 90 min after burn; (f) 120 min after burn
    • Table 1. Systematic clustering classification accuracy

      View table

      Table 1. Systematic clustering classification accuracy

      Period after burn /minAccuracy /%
      583.33
      1081.33
      30100
      60100
      90100
      120100
    • Table 2. Factor loading for optical parameters

      View table

      Table 2. Factor loading for optical parameters

      Optical parameterFAC1FAC2
      μa for R wavelength0.930-0.143
      μa for G wavelength0.960-0.173
      μa for B wavelength0.818-0.419
      μs' for R wavelength-0.3160.923
      μs' for G wavelength-0.2150.971
      μs' for B wavelength-0.1580.976
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    Xiaoxue Zhong, Guowu Huang, Hongbo Miu, Chenghao Hu, Wei Liu, Chunrong Sun, Zhihua Chen, Gangning Li, Zili Cao, Xin Jin, Weihao Lin. Noninvasive Quantitative Assessment of Burn Degree Based on Spatial Frequency-Domain Imaging[J]. Chinese Journal of Lasers, 2022, 49(24): 2407205

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    Paper Information

    Category: Biomedical Optical Imaging

    Received: Jul. 4, 2022

    Accepted: Sep. 22, 2022

    Published Online: Nov. 15, 2022

    The Author Email: Lin Weihao (lwhlucky@126.com)

    DOI:10.3788/CJL202249.2407205

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