Research Progress on Cuproptosis in Tumor Therapy and Its Applications

WANG Jiaqi; CHENG Fang

doi:10.12046/j.issn.1000-5277.2024050065

Journal of Fujian Normal University(Natural Science Edition), Volume. 41, Issue 4, 49(2025)

Research Progress on Cuproptosis in Tumor Therapy and Its Applications

WANG Jiaqi and CHENG Fang^*

Author Affiliations

School of Materials Science and Engineering, Nanjing University of Posts and Telecommunications, Nanjing 210023, China

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Abstract Get PDF(in Chinese)

This review summarizes the mechanisms of cuproptosis, examines key factors in the tumor microenvironment that limit its occurrence, highlights recent advances in the use of nanomaterials to trigger cuproptosis and enhance cancer treatment efficacy, and explores future research directions in this area. These insights offer new ideas for expanding the application of nanomaterials in cancer treatment.

Keywords

combination therapy copper ionophores cuproptosis nanomaterials programmed cell death tumor therapy

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WANG Jiaqi, CHENG Fang. Research Progress on Cuproptosis in Tumor Therapy and Its Applications[J]. Journal of Fujian Normal University(Natural Science Edition), 2025, 41(4): 49

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Paper Information

Received: May. 29, 2024

Accepted: Aug. 21, 2025

Published Online: Aug. 21, 2025

The Author Email: CHENG Fang (iamfcheng@niupt.edu.cn)

DOI:10.12046/j.issn.1000-5277.2024050065

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