Compared with noble metal nanoparticles, all-dielectric nanoparticles have attracted much attention because of their support to Mie resonance with low loss in optical frequencies, which have been the important material in nanophotonics to enhance the interaction between light and matter. Semiconductor nanoparticles with high refractive indexes are important all-dielectric nanoparticles, which support both electrical and magnetic resonances and can be used to construct low-loss metamaterials and metasurfaces in optical frequencies. Based on the recent research on semiconductor sub-wavelength particles with high refractive indexes, the related works and applications of the fluorescence manipulation of semiconductor micro-nano particles based on Mie resonance are mainly introduced, and the development of this field is prospected.