Dosimetric effect of multi-leaf collimator angle change on the left-sided breast hypofractionated radiotherapy with simultaneous integrated boost

Che CHEN; Rui CHEN; Zhijiang LU; Dehong LUO

doi:10.11889/j.1000-3436.2022-0141

Journal of Radiation Research and Radiation Processing, Volume. 41, Issue 4, 040302(2023)

Dosimetric effect of multi-leaf collimator angle change on the left-sided breast hypofractionated radiotherapy with simultaneous integrated boost

Che CHEN, Rui CHEN, Zhijiang LU, and Dehong LUO^*

Author Affiliations

Cancer Clinical Medical Center, Radiation Oncology Center, the First People Hospital of Zunyi/ the Third Affiliated Hospital of Zunyi Medical University, Zunyi 563099, China

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Figures & Tables(5)

Fig. 1. Multi-leaf collimator with 0°: (a) and parallel to the long axis of PTV; (b) PTV-blue, PGTV-red (color online)

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Table 1. Volume of PGTV and PTV
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Table 1. Volume of PGTV and PTV
内侧瘤床
Medial tumor bed
中间瘤床
Central tumor bed
外侧瘤床
Lateral tumor bed
F p
PGTV 62.95±37.17 56.14±16.79 63.24±29.34 0.38 0.68
PTV 664.30±219.41 679.56±302.47 657.42±237.91 0.04 0.96

Table 2. Comparison for target dosimetry parameters

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Table 2. Comparison for target dosimetry parameters

参数 Parameter		内侧瘤床 Medial tumor bed			中间瘤床 Central tumor bed			外侧瘤床 Lateral tumor bed
参数 Parameter		Plan-A	Plan-O	p	Plan-A	Plan-O	p	Plan-A	Plan-O	p
PGTV	V_处方/%	96.68±1.17	96.70±1.13	0.92	98.22±1.18	98.19±1.03	0.83	98.37±1.05	98.41±1.16	0.70
	CI	0.52±0.08	0.52±0.07	0.93	0.53±0.07	0.53±0.06	0.57	0.56±0.09	0.56±0.09	0.73
	HI	1.06±0.01	1.06±0.01	0.72	1.05±0.01	1.05±0.01	0.58	1.05±0.01	1.05±0.01	0.67
PTV	V_处方/%	96.97±1.20	97.21±1.19	0.12	96.95±0.84	97.11±0.85	0.11	96.91±1.05	97.11±1.00	0.28
	CI	0.75±0.06	0.75±0.06	1.00	0.77±0.06	0.77±0.06	0.07	0.77±0.05	0.77±0.05	0.48
	HI	1.21±0.01	1.22±0.01	0.49	1.21±0.01	1.21±0.01	0.65	1.21±0.02	1.21±0.01	0.33

Table 3. Dose comparison for the left lung

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Table 3. Dose comparison for the left lung

参数 Parameter	内侧瘤床 Medial tumor bed			中间瘤床 Central tumor bed			外侧瘤床 Lateral tumor bed
参数 Parameter	Plan-A	Plan-O	p	Plan-A	Plan-O	p	Plan-A	Plan-O	p
V₅/ %	51.14±6.12	52.43±5.63	0.005	46.12±3.12	45.93±3.43	0.68	45.60±6.22	46.15±6.21	0.31
V₁₀/ %	38.07±6.31	39.06±6.33	0.01	31.33±3.03	31.29±2.85	0.93	33.23±6.19	33.72±6.27	0.32
D_mean/ Gy	11.10±1.53	11.35±1.57	0.02	9.98±0.61	9.87±0.75	0.21	9.85±1.36	10.07±1.31	0.07

Table 4. Dose comparison for the heart and LAD

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Table 4. Dose comparison for the heart and LAD

参数 Parameter		内侧瘤床 Medial tumor bed			中间瘤床 Central tumor bed			外侧瘤床 Lateral tumor bed
参数 Parameter		Plan-A	Plan-O	p	Plan-A	Plan-O	p	Plan-A	Plan-O	p
Heart	V₈ / %	22.22±7.04	22.78±7.65	0.01	19.77±7.23	19.76±7.04	0.95	17.93±3.54	17.91±3.48	0.95
	D_mean/ Gy	6.30±2.32	6.52±2.49	0.02	5.36±1.51	5.37±1.46	0.81	5.14±1.06	5.22±1.03	0.23
LAD	D_max / Gy	30.11±10.43	31.12±9.87	0.02	25.00±11.88	25.53±11.17	0.07	29.07±7.62	29.63±7.57	0.004
	D_mean / Gy	20.25±7.16	20.93±7.01	0.005	18.05±8.19	17.76±7.05	0.62	18.38±6.78	18.86±6.80	0.001

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Che CHEN, Rui CHEN, Zhijiang LU, Dehong LUO. Dosimetric effect of multi-leaf collimator angle change on the left-sided breast hypofractionated radiotherapy with simultaneous integrated boost[J]. Journal of Radiation Research and Radiation Processing, 2023, 41(4): 040302

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