Multi-Objective Optimization for Laser Closure Process Parameters <italic>in vitro</italic> Skin Tissue Based on NSGA-Ⅱ

Jun Huang; Zibo Chen; Qimeng Liu; Cong Li; Kehong Wang

doi:10.3788/CJL201946.0207001

Chinese Journal of Lasers, Volume. 46, Issue 2, 0207001(2019)

Multi-Objective Optimization for Laser Closure Process Parameters in vitro Skin Tissue Based on NSGA-Ⅱ

Jun Huang^1,2、*, Zibo Chen¹, Qimeng Liu¹, Cong Li¹, and Kehong Wang^1,2

¹ School of Material Science and Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China

² Key Laboratory for Controlled Arc Intelligent Material Additive Technology, Ministry of Industry Informatization, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China

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Figures & Tables(10)

Fig. 1. (a) Experimental tissue sample; (b) experiment setup

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Fig. 2. Flow chart of the NSGA-Ⅱ

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Fig. 3. Pareto-optimal front for incision tensile strength and tissue temperature

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Fig. 4. Appearances of in vitro pigskin tissue closure with optimized parameters. (a) Front side; (b) reverse side; (c) cross-section

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Fig. 5. Micrograph of laser closure in vitro pigskin tissue

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Table 1. Experimental parameters and results

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Table 1. Experimental parameters and results

Number	PowerP /W	Speed v /(mm·s^-1)	FrequencyF /kHz	Tensile strengthσ_b /(N·cm^-2)	Peak temperatureT /℃
1	3.5	250	150	38.2	49.2
2	4	200	50	27.3	53.0
3	3	150	50	40.2	50.0
4	4	250	100	28	53.5
5	4	150	100	36.7	58.0
6	3.5	200	100	43.8	53.5
7	3	250	50	37.5	49.0
8	3	150	100	22.1	42.0
9	3	250	100	27.2	39.8
10	3.5	200	100	45.7	52.7
11	3	200	50	27.3	40.8
12	3.5	150	150	28.9	53.3
13	4	200	150	44.7	56.5
14	3.5	200	100	45.9	53.1
15	3.5	200	100	42.4	54.5
16	3	200	150	23.6	40.8
17	3.5	200	100	45	54.2

Table 2. Value range of process parameters
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Table 2. Value range of process parameters
Welding parameters Value
P /W 3 3.5 4
v /(mm·s^-1) 150 200 250
F /kHz 50 100 150

Table 3. Pareto-optimal solution

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Table 3. Pareto-optimal solution

Number	Laser powerP /W	Laser frequencyF /kHz	Welding speedv /(mm·s^-1)	Tensile strengthσ_b /(N·cm^-2)	Tissue temperatureT /℃
1	3.65	119.81	205.33	44.79	53.29
2	3.57	121.41	220.97	44.23	53.57
3	3.59	129.36	216.52	44.42	53.87

Table 4. Sensitivity of the response of objective functions to the decision variables
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Table 4. Sensitivity of the response of objective functions to the decision variables
Parameter Range /% Δσ_b /(N·cm^-2) ΔT_p /℃
ΔP /W +10-10 +4.1-3.2 +3.5-4.5
Δv /(mm·s^-1) +10-10 +3.4-3.0 +0.50-0.80
ΔF /kHz +10-10 +2.1-2.4 +0.6-0.4

Table 5. Experimental verification results
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Table 5. Experimental verification results
Number 1 2 3 4 5 Average
σ_b /(N·cm^-2) 47.9 47.7 46.3 45.1 46.5 46.7
T /℃ 51.2 52.5 49.3 48.6 52.4 50.8

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Jun Huang, Zibo Chen, Qimeng Liu, Cong Li, Kehong Wang. Multi-Objective Optimization for Laser Closure Process Parameters in vitro Skin Tissue Based on NSGA-Ⅱ[J]. Chinese Journal of Lasers, 2019, 46(2): 0207001

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