[1] [1] TAKAHASHI Y, TAKESUE Y, FUJIWARA M, et al. Risk factors for surgical site infection after major hepatobiliary and pancreatic surgery[J]. J Infect Chemother, 2018, 24(9): 739-743.

[5] [5] ADAM U, MAKOWIEC F, RIEDIGER H, et al. Risk factors for complications after pancreatic head resection[J]. Am J Surg, 2004, 187(2): 201-208.

[6] [6] BARRETO S G, SINGH M K, SHARMA S, et al. Determinants of surgical site infections following pancreatoduodenectomy[J]. World J Surg, 2015, 39(10): 2557-2563.

[7] [7] ZHANG L, LIAO Q, ZHANG T, et al. Blood transfusion is an independent risk factor for postoperative serious infectious complications after pancreaticoduodenectomy[J]. World J Surg, 2016, 40(10): 2507-2512.

[8] [8] BADIA J M, CASEY A L, PETROSILLO N, et al. Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries[J]. J Hosp Infect, 2017, 96(1): 1-15.

[9] [9] VALLE J W, PALMER D, JACKSON R, et al. Optimal duration and timing of adjuvant chemotherapy after definitive surgery for ductal adenocarcinoma of the pancreas: ongoing lessons from the ESPAC-3 study[J]. J Clin Oncol, 2014, 32(6): 504-512.

[10] [10] FANG Y, GURUSAMY K S, WANG Q, et al. Pre-operative biliary drainage for obstructive jaundice[J]. Cochrane Database Syst Rev, 2012, 2012(9): CD005444.

[11] [11] HORAN T C, ANDRUS M, DUDECK M A. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting[J]. Am J Infect Control, 2008, 36(5): 309-332.

[12] [12] ALKAAKI A, AL-RADI O O, KHOJA A, et al. Surgical site infection following abdominal surgery: a prospective cohort study[J]. Can J Surg, 2019, 62(2): 111-117.

[13] [13] BASSI C, MARCHEGIANI G, DERVENIS C, et al. The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 years after[J]. Surgery, 2017, 161(3): 584-591.

[14] [14] DINDO D, DEMARTINES N, CLAVIEN P A. Classification of surgical complications: a new proposal with evaluation in a cohort of 6 336 patients and results of a survey[J]. Ann Surg, 2004, 240(2): 205-213.

[15] [15] WENTE M N, BASSI C, DERVENIS C, et al. Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)[J]. Surgery, 2007, 142(5): 761-768.

[16] [16] BESSELINK M G, VAN RIJSSEN L B, BASSI C, et al. Definition and classification of chyle leak after pancreatic operation: a consensus statement by the International Study Group on Pancreatic Surgery[J]. Surgery, 2017, 161(2): 365-372.

[17] [17] WENTE M N, VEIT J A, BASSI C, et al. Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition[J]. Surgery, 2007, 142(1): 20-25.

[18] [18] LA TORRE M, ZIPARO V, NIGRI G, et al. Malnutrition and pancreatic surgery: prevalence and outcomes[J]. J Surg Oncol, 2013, 107(7): 702-708.

[19] [19] PEDRAZZOLI S. Pancreatoduodenectomy (PD) and postoperative pancreatic fistula (POPF): a systematic review and analysis of the POPF-related mortality rate in 60 739 patients retrieved from the English literature published between 1990 and 2015[J]. Medicine (Baltimore), 2017, 96(19): e6858.

[20] [20] SCHORN S, DEMIR I E, VOGEL T, et al. Mortality and postoperative complications after different types of surgical reconstruction following pancreaticoduodenectomy—a systematic review with Meta-analysis[J]. Langenbecks Arch Surg, 2019, 404(2): 141-157.

[21] [21] SUGIURA T, UESAKA K, OHMAGARI N, et al. Risk factor of surgical site infection after pancreaticoduodenectomy[J]. World J Surg, 2012, 36(12): 2888-2894.

[22] [22] ZHANG H, PATEL S A, KANDIL E, et al. Pancreatic elastase is proven to be a mannose-binding protein—implications for the systemic response to pancreatitis[J]. Surgery, 2003, 133 (6): 678-688.

[23] [23] YAMASHITA K, KATO D, SASAKI T, et al. Contaminated drainage fluid and pancreatic fistula after pancreatoduodenectomy: a retrospective study[J]. Int J Surg, 2018, 52: 314-319.

[24] [24] TRAVERSO L W, MACFARLANE S K. Pancreatic juice in the peritoneal cavity: antibiotics or omental preservation prevent mortality[J]. J Surg Res, 1987, 43(3): 220-225.

[25] [25] WHIPPLE A O, PARSONS W B, MULLINS C R. Treatment of carcinoma of the ampulla of vater[J]. Ann Surg, 1935, 102 (4): 763-779.

[26] [26] SCHEUFELE F, SCHORN S, DEMIR I E, et al. Preoperative biliary stenting versus operation first in jaundiced patients due to malignant lesions in the pancreatic head: a Meta-analysis of current literature[J]. Surgery, 2017, 161(4): 939-950.

[27] [27] CORTES A, SAUVANET A, BERT F, et al. Effect of bile contamination on immediate outcomes after pancreaticoduodenectomy for tumor[J]. J Am Coll Surg, 2006, 202(1): 93-99.

[28] [28] JAGANNATH P, DHIR V, SHRIKHANDE S, et al. Effect of preoperative biliary stenting on immediate outcome after pancreaticoduodenectomy[J]. Br J Surg, 2005, 92(3): 356-361.

[29] [29] POVOSKI S P, KARPEH M S JR, CONLON K C, et al. Preoperative biliary drainage: impact on intraoperative bile cultures and infectious morbidity and mortality after pancreaticoduodenectomy[J]. J Gastrointest Surg, 1999, 3(5): 496-505.

[30] [30] SATO A, MASUI T, NAKANO K, et al. Abdominal contamination with Candida albicans after pancreaticoduodenectomy is related to hemorrhage associated with pancreatic fistulas[J]. Pancreatology, 2017, 17(3): 484-489.

[31] [31] SUN Y L, ZHAO Y L, LI W Q, et al. Total closure of pancreatic section for end-to-side pancreaticojejunostomy decreases incidence of pancreatic fistula in pancreaticoduodenectomy[J]. Hepatobiliary Pancreat Dis Int, 2017, 16(3): 310-314.

[32] [32] KAISER A B, HERRINGTON J L JR, JACOBS J K, et al. Cefoxitin versus erythromycin, neomycin, and cefazolin in colorectal operations. Importance of the duration of the surgical procedure[J]. Ann Surg, 1983, 198(4): 525-530.

[33] [33] COPPA G F, ENG K. Factors involved in antibiotic selection in elective colon and rectal surgery[J]. Surgery, 1988, 104 (5): 853-858.

[34] [34] HOOTON T M, HALEY R W, CULVER D H, et al. The joint associations of multiple risk factors with the occurrence of nosocomial infection[J]. Am J Med, 1981, 70(4): 960-970.

[35] [35] BEHRMAN S W, ZARZAUR B L. Intra-abdominal sepsis following pancreatic resection: incidence, risk factors, diagnosis, microbiology, management, and outcome[J]. Am Surg, 2008, 74(7): 572-579.