Chinese Optics Letters, Volume. 13, Issue 5, 051701(2015)

Fluorochrome-labeled monoclonal antibody with characteristic M-shaped spectral peak for optical imaging: Dual-labeling versus mixture of fluorochromes

Jan Menke*, Thomas Kruewel, and Christian Dullin
Author Affiliations
  • Institute for Diagnostic and Interventional Radiology, University Medical Center, Georg August University, 37075 Goettingen, Germany
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    Figures & Tables(3)
    Multispectral fluorescence emission measurements.
    Fluorescence intensity of Probe C594/680 versus Probe D594+680.
    • Table 1. Fluorochrome-Labeled Monoclonal Antibody Probes

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      Table 1. Fluorochrome-Labeled Monoclonal Antibody Probes

      ProbeAbsorption Peak(s) (nm)Emission Peak(s) (nm)Cetuximab (Erbitux)Alexa Fluor 594Alexa Fluor 680
      A5945906171 mgOne vial
      B6806797021 mgOne vial
      C594/680590+679617+7022 mgOne vialOne vial
      D594+680590+679617+702Mix equal volumes of Probes A+B
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    Jan Menke, Thomas Kruewel, Christian Dullin, "Fluorochrome-labeled monoclonal antibody with characteristic M-shaped spectral peak for optical imaging: Dual-labeling versus mixture of fluorochromes," Chin. Opt. Lett. 13, 051701 (2015)

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    Paper Information

    Category: Medical optics and biotechnology

    Received: Oct. 15, 2014

    Accepted: Mar. 26, 2015

    Published Online: Sep. 20, 2018

    The Author Email: Jan Menke (Menke-J@T-Online.de)

    DOI:10.3788/COL201513.051701

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