Laser & Optoelectronics Progress, Volume. 62, Issue 18, 1817012(2025)
Bloch Surface Wave Detection Technology and Its Biomedical Applications (Invited)
Fig. 1. Transmission characteristics of the PBG structure. (a) Schematic diagram of a 1D PBG structure; (b) dispersion diagram of frequency vs. wavevector for the p-polarized light[4]
Fig. 8. Schematics of BSW label-free sensing detection[52]. (a) Detection principle; (b) reflectance spectrum
Fig. 9. High-throughput detection results of BSW under label-free condition[59]. (a) 384-spot microarray image displayed in natural colors; (b) 96-spot microarray image displayed in pseudo-color
Fig. 11. Experimental setup of BSW biosensing detection based on a D-shaped optical fiber[61]. (a) SEM image of the sensing structure; (b) optical properties of two dielectric materials; (c) experimental setup for optical property characterization; (d) experimental setup for biological sample detection
Fig. 12. Dual-mode detection of miRNA using label-free and fluorescence methods[62]. (a) Schematic diagram of sensor chip functionalization; (b) schematic of label-free detection principle; (c) schematic of fluorescence detection principle; (d) real-time monitoring of binding kinetics
Fig. 13. Dual-mode detection of VEGF using label-free and fluorescence methods[67]. (a) Schematic of the experimental principle; (b) photograph of the disposable BSW biosensor chip; (c) functionalized surface of the chip; (d) reflectivity map in label-free mode; (e) fluorescence detection result
Fig. 14. Dual-mode detection of SARS-CoV-2 antibody using label-free and fluorescence methods[68]. (a) Schematic diagram of disposable PBG chip and its microfluidic components; (b) schematic diagram of PBG chip structure
Fig. 15. Schematics of BSW-ARI imaging technology[73]. (a) Experimental setup; (b) schematic of ARI; (c) BFP image of BSW; (d) SEM image of nanoparticles; (e) BSW-ARI imaging result
Fig. 16. Comparison between traditional microscopy and BSW-enhanced microscopy[74]. (a) Reference image; (b) imaging result of traditional microscopy; (c) imaging result of BSW-enhanced microscopy; (d) magnified view of traditional microscopy image; (e) Fourier transform of traditional microscopy image; (f) Fourier transform of BSW-enhanced microscopy image; (g) magnified view of BSW-enhanced microscopy image; (h) lateral intensity profile of a single microsphere; (i) lateral intensity profile of two adjacent microspheres
Fig. 17. Schematic diagrams of BSW-SIM imaging technology[75]. (a) Imaging diagram; (b) diagram of energy band structure; (c) diagram of spatial frequency extension; (d) top view of PBG structure
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Shuna Li, Yuhang Wan, Yanyu Zhao. Bloch Surface Wave Detection Technology and Its Biomedical Applications (Invited)[J]. Laser & Optoelectronics Progress, 2025, 62(18): 1817012
Category: Medical Optics and Biotechnology
Received: May. 14, 2025
Accepted: Jun. 5, 2025
Published Online: Sep. 15, 2025
The Author Email: Yuhang Wan (yuhangwan@buaa.edu.cn), Yanyu Zhao (yanyuzhao@buaa.edu.cn)
CSTR:32186.14.LOP251227