Most of the biomolecules in living organisms are chiral.The chiral conformation of biomolecules can be transferred to plasmonic nanocrystals via coupling with its localized surface plasmon resonance (LSPR),inducing a new circular dichroic peak at the LSPR position of plasmonic nanocrystals.In this review,chiral plasmonic nanocrystal is defined as they can possess the chiroptical activity.Because of its high stability and reproducible chiroptical response signal,chiral plasmonic nanocrystals have attracted great attention from basic science to applications.So far,synthesis of chiral plasmonic nanocrystals have always been hot topic in the numerous fields,such as,bio-/chemical sensing,circular polarizers,photocatalysis,cancer treatment,etc.In this review,chiral molecules on the surface of plasmonic nanocrystals inducing chiroptical response are not discussed because their weak coupling strength leads to weak chiroptical activity.We will focus on the recent fabrication technologies of chiral plasmonic nanocrystals,including (i) self-assembly of achiral plasmonic nanocrystals by chiral molecules or soft templates; (ii) chiral molecules encapsulation into a single nanocrystal is to make core-shell chiral plasmonic nanocrystal; (iii) chiral conformation of chiral molecules transferring to the structure of plasmonic nanocrystals is to fabricate a single helical chiral plasmonic nanocrystal.Finally,we have summarized and prospected the synthetic nanotechnology of chiral plasmonic nanocrystals based on the recent research achievements.