Fig. 1. Molecular structure of GlA

Fig. 2. COM microscopy images， diagram of crystal habit and their XRD patterns in the presence of different concentrations of GlA.（a） XRD patterns； （b） diagram of COM crystal habit in the absence of GlA； （c）~（h） microscopic crystal morphology images of COM at GlA concentrations of 0， 10， 30， 50， 100 and 200 μg/mL， respectively

Fig. 3. Quantitative statistics of the size and morphology of COM crystals at different concentrations of GlA.（a） Variation of （100） crystal area of COM with GlA concentration； （b） plot of the thickness of COM as a function of GlA concentration； （c） aspect ratio of COM as a function of GlA concentration

Fig. 4. Relationship between the inhibition effect of COM crystallization and the concentration of GlA.（a） Calcium ISE measurements of COM crystallization in the presence of GlA at varying concentrations； （b） percentage inhibition of COM crystallization by GlA

Fig. 5. Crystal growth rate of COM with GlA concentration.（a） Schematic diagram of COM single crystal （left） and contact cross dual crystal （right）； （b）~（e） COM microscope images at 0 h and microscope images with the addition of 0 and 200 μg/mL GlA for 3 h；（f） relative growth rates of COM along ［001］， ［010］ and ［100］ at different GlA concentrations （data are reported as the average of more than 20 crystals from 3 separate batches， the error bar is equal to two standard deviations）

Fig. 6. Schematic diagram of the atomic arrangement of the （100）， （010）， （021） and （121¯） plane of COM crystal and their interaction with GlA

Fig. 7. Schematic diagram of GlA's inhibition of COM crystallization