Biological Effects of Light-Emitting Diode Light Sources and their Progress in Clinical Research

Tiantian Hu; Jinpeng Wu; Huijuan Yin; Qinlao Yang; Jun Wang

doi:10.3788/LOP56.120003

Laser & Optoelectronics Progress, Volume. 56, Issue 12, 120003(2019)

Biological Effects of Light-Emitting Diode Light Sources and their Progress in Clinical Research

Tiantian Hu^1,2, Jinpeng Wu³, Huijuan Yin³, Qinlao Yang², and Jun Wang^1、*

Author Affiliations

¹ School of Medicine, Shenzhen University, Shenzhen, Guangdong 518071, China

² Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong 518060, China

³ Laser Medicine Laboratory, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China;

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Figures & Tables(2)

Fig. 1. Tissue penetration depths of LED light sources with different wavelengths

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Table 1. Characteristics of LED light sources with different wavelengths

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Table 1. Characteristics of LED light sources with different wavelengths

Characteristic	Blue	Green	Yellow	Red	Near-infrared	Combined
Wavelength /nm	400-470	510-570	570-600	630-780	800-1200	Variable
Depth of LEDlightpenetration /mm	<1	0.5-2	0.5-2	2-4	5-10	Variable
Deepest target	Epidermis	Epidermis	Papillary dermis	Adnexa	Adnexa andreticular dermis	Variable
Commonly usedwavelength /nm	415, 420, 425, 445, 453, 470	525, 530	590	605, 625, 630, 632, 633, 650, 660, 680	820, 830, 855, 880, 860, 890	Variable
Power density /(mW∙cm^-2)	0.065 -50	3.5-10	4.0	1.3-500	5-10	Variable

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Tiantian Hu, Jinpeng Wu, Huijuan Yin, Qinlao Yang, Jun Wang. Biological Effects of Light-Emitting Diode Light Sources and their Progress in Clinical Research[J]. Laser & Optoelectronics Progress, 2019, 56(12): 120003

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Paper Information

Category: Reviews

Received: Nov. 27, 2018

Accepted: Jan. 21, 2019

Published Online: Jun. 13, 2019

The Author Email: Wang Jun (yxywj@szu.edu.cn)

DOI:10.3788/LOP56.120003

Topics

laser devices and laser physics

Lasers and Laser Optics

Laser physics

laser manufacturing

Instrumentation, Measurement and Metrology