Laser & Optoelectronics Progress, Volume. 57, Issue 18, 180001(2020)

Progress of Point Scanning Super-Resolution Microscopy Based on Frequency Shifting

Yuchen Chen1, Chuankang Li1, Xiang Hao1, Cuifang Kuang1,2,3、*, and Xu Liu1,2
Author Affiliations
  • 1State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, China
  • 2Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan, Shanxi 0 30006, China
  • 3Ningbo Research Institute, Zhejiang University, Ningbo, Zhejiang 315100, China
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    Figures & Tables(9)
    Schematic diagram of parallel detection system[24]. Inset Ⅰ is diagram of detector array composed of 32 point-detectors. GM: Galvo mirror; M: mirror; SL: scanning lens; TL: tube lens; OL: objective lens; S: sample; DM: dichroic mirror; BPF: bandpass filter; L: lens; DA: detector array
    Cross sections of effective PSF at distance vd from optical axis in parallel detection technology. Blue curve represents PSF of common confocal microscopy, red curve is PSF at center of optical axis, and black curve stands for PSF at different distances from optical axis[25]. (a) Peak intensity of black curve decreases with increasing vd and moves to side; (b) effective PSF is shifted to peak value on axis; (c)
    All-optical realizations of parallel detection. (a) Rescan system[29]; (b) OPRA system[23]
    Diagrams of SPIN and SPADE systems[45]. (a) SPIN system; (b) SPADE system
    Schematic of VIKMOM and its decoding procedure for super-resolution image recovery[49]. (a) Principle of imaging system; (b) decoding procedure for super-resolution image recovery
    Multifocal saturated virtual modulation microscopy. (a) Scanning process of LSM; (b) multiple focal spot detection system; (c) procedure for virtual modulation[50]
    Laser scanning SSIM imaging. (a) Diagram of laser scanning SSIM setup; (b) phase modulation pattern on SLM and corresponding scanning route[51]
    Working principle and imaging results of NFOMM[33]. (a) Diagram of focal spot modulation; (b) PSF and OTF; (c) profiles of OTF; (d) imaging results of spoke-like sample; (e)(f) dual-color imaging results of NFOMM and standard confocal microscopy for Vero cells
    Nonlinear focal modulation microscopy based on interleaved reconstruction. (a) Schematic of interleaved reconstruction algorithm; (b) schematic of SIFM
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    Yuchen Chen, Chuankang Li, Xiang Hao, Cuifang Kuang, Xu Liu. Progress of Point Scanning Super-Resolution Microscopy Based on Frequency Shifting[J]. Laser & Optoelectronics Progress, 2020, 57(18): 180001

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    Paper Information

    Category: Reviews

    Received: Apr. 27, 2020

    Accepted: Jun. 4, 2020

    Published Online: Sep. 2, 2020

    The Author Email: Kuang Cuifang (cfkuang@zju.edu.cn)

    DOI:10.3788/LOP57.180001

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