Laser & Optoelectronics Progress, Volume. 61, Issue 6, 0618009(2024)
Noncoherent Raman Spectroscopy and Its Biomedical Application (Invited)
Raman spectroscopy has the advantages of being noninvasive, fingerprint free, water background free, simple sampling preparation, and high spectral resolution; therefore, it has become a popular analytical technique in many research fields. In particular, the Raman spectroscopy can intrinsically capture biochemical information related to normal physiology or abnormal pathology in biomedicine. Additionally, various biological and clinical samples, such as cells, tissues, body fluids, and microbiology can be easily studied using the Raman spectroscopy without complex sample preparation. Thus far, the Raman spectroscopy has shown its high potential for biomedical applications. This review mainly includes an introduction to the basic mechanisms of spontaneous Raman and surface-enhanced Raman scatterings, followed by a description of the analysis procedures and algorithms for obtaining Raman data (spectral and imaging). Further, a brief summary of the applications of noncoherent Raman microscopy in biomedicine in recent years is presented, and its current challenges and future directions are discussed.
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Yuyi Li, Yue Gan, Ben Niu, Jing Huang, Qiuqiang Zhan. Noncoherent Raman Spectroscopy and Its Biomedical Application (Invited)[J]. Laser & Optoelectronics Progress, 2024, 61(6): 0618009
Category: Microscopy
Received: Feb. 5, 2024
Accepted: Feb. 19, 2024
Published Online: Mar. 18, 2024
The Author Email: Huang Jing (jing_huang@scnu.edu.cn), Zhan Qiuqiang (zhanqiuqiang@m.scnu.edu.cn)