In order to avoid the environmental pollution and damage to operators caused by the use of chemical reagents for wheel set paint removal, an automatic paint removal method based on composite laser is proposed. The equipment adopts the through design, and the runner mechanism cooperates with the system scheme of three-axis automation platform to meet the requirements of on-site process layout and assembly line operation. Through theoretical calculation, effect test, efficiency test and SEM test, the specific process parameters are pulse laser power 100%, scanning speed 8 000 mm/s, line width 55 mm, frequency 20 kHz and wheel set rotation speed 21 mm/s. The power of semiconductor laser is 90%, the scanning speed is 7 000 mm/s, the line width is 55 mm, the frequency is 2 kHz, the duty cycle is 100%, and the transverse moving speed of laser processing head is 1.95 mm/s.