Journal of Forensic Medicine, Volume. 41, Issue 2, 136(2025)

Research Status of Caenorhabditis elegans Model in Toxicology and Its Applications in Forensic Science

LI Zhuo, ZENG Yi-ru, SHU Zhi-long, SUN Xue-hong, and ZHANG Kui*
Author Affiliations
  • West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu 610041, China
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    Caenorhabditis elegans, as an emerging model organism, has been widely used in multiple disciplines such as medicine, life science, and environmental science in recent years, due to its characteristics of short life cycle, clear genetic background, highly conserved evolution, complete genome analysis and excellent fitting between experimental data and human results. It also shows unique advantages in the field of toxicology. This paper summarizes its advantages in toxicological research starting from the biological characteristics of C. elegans, introduces the toxicological research methods and progress based on the C. elegans model, focuses on demonstrating its applications in environmental forensic medicine and forensic toxicology, and looks forward to the application of the relevant results in the field of forensic science.

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    LI Zhuo, ZENG Yi-ru, SHU Zhi-long, SUN Xue-hong, ZHANG Kui. Research Status of Caenorhabditis elegans Model in Toxicology and Its Applications in Forensic Science[J]. Journal of Forensic Medicine, 2025, 41(2): 136

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    Paper Information

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    Received: Apr. 14, 2024

    Accepted: Aug. 25, 2025

    Published Online: Aug. 25, 2025

    The Author Email: ZHANG Kui (zhk@scu.edu.cn)

    DOI:10.12116/j.issn.1004-5619.2024.440406

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