A low power consumption telemetry capsule was designed for monitoring the gastrointestinal tract’s parameters in long-term and continuation. The capsule consisted of a sensor module, a low power consumption special integrated chip and a wireless emission module mainly. First, to reduce the integrated chip power consumption, a three-state clock management unit was used to choose the appropriate clock frequency for the internal modules of the integrated chip and to shut down the clocks of correcting idle modules. Then, the simplex communication, data temporary storage, reducing transmitting power, etc, were used to reduce the power consumption of the RF module. Finally, the capsule was controlled at work intermittently by the software to reduce the system overall power consumption. Test results show that the work current of the special integrated chip is about 300 μ A @ 2 MH and its dormancy current is about 4 μ A @ 28 kHz. Furthermore, the emission current from the RF module is about 12 mA, and the current of collecting data by a microcontroller is about 300 μ A. As compared with the second generation parameter capsule, the power consumptions of the RF module and the microcontroller are reduced by about 47% and 24% , respectively, and the work time is about 136 h continuously, which basically meets the demands of the capsules for monitoring the gastrointestinal tract’s parameters in long-term and continuation.