High resolution tomography images of human ex vivo kidney and colon tissues are obtained by using full-field optical coherence tomography (FFOCT) system. The experimental setup is based on a Linnik-type interferometer illuminated by a low coherence lamp. The theoretical resolution of the system is 0.5 μm. Series of interferometric images of sample and reference mirror are obtained by a charge-coupled device (CCD) and four-step phase-shifting algorithm. This experimental setup is used to image human kidney, and kidney tissue structures are successfully identified based on characteristic of histological slices of the kidney. The system is used to image human colon tissue and colonic adenocarcinoma tissue. On the basis of histological slices images, the ability of the FFOCT system identifying human cancer tissue is verified with the analysis of the colonic tissue and colonic adenocarcinoma tissue tomography images. The results of the study lay the foundation for future clinical diagnosis and application for FFOCT.