Ho3+/Yb3+codoped oxyfluoride silicate glass has been prepared. According to DTA studies, the as-made glass was crystallized. X-ray diffraction (XRD), absorption spectrum and up-conversion luminescence of glass ceramics were measured. The results show: Intense green (544 nm) and red (656 and 748 nm) emissions corresponding to the transitions 5F4/5S2→5I8,5F4/5S2→5I7 and 5F5→5I8 of Ho3+, respectively, were simultaneously observed at room temperature under 980 nm LD excitation. Compared to the as-made glass, the Ho3+ -Yb3+codoped transparent glass ceramics containing BaF2 nanocrystals exhibited highly efficient up-conversion luminescence. Especially, the green emission intensity greatly enhanced about nearly 347 times. The studied results indicate that the oxyfluoride silicate glass ceramics containing BaF2 nanocrystals is a kind of potential luminescence materials for upconversion green lasers.