Due to the properties of real-time, medium-free, and non-invasive, the optical Doppler effect based non-invasive blood flow measurement is valuable and has a promising future in clinical and other fields. At present, there are three optical non-invasive blood flow measurement technologies: laser Doppler blood flow measurement technology, optical coherence tomography Doppler imaging technology, and photo-acoustic Doppler blood flow measurement technology. The principles of the above three technologies were briefly analyzed, the respective development status was described, and the future and development of these new technologies were exhibited.