Molybdenum telluride (MoTe₂), a transition metal dichalcogenide, possesses a narrow band gap (0.9 eV) and high electron mobility, demonstrating good application prospects in infrared optoelectronics. MoTe₂ is a two-dimensional layered crystal structure combined by van der Waals forces. It is a reliable method to prepare MoTe₂ quantum dots and nanosheets by liquid phase exfoliation. The kinds of solvent used in the liquid phase exfoliation method play an important role in the preparation process. However, in the related reports, studies about the effect of solvents on the exfoliation effect are rare. Therefore, it is significant to explore the best solvent of liquid phase exfoliation for the preparation of MoTe₂ quantum dots.Six kinds of different solvents (1-methyl-2-pyrrolidone, 1-vinyl-2-pyrrolidone, acetone, ethanol, dimethylformamide, isopropanol) were added to MoTe₂ powder by ultrasonic-assisted liquid phase exfoliation method. The mixed solution was sonicated at 210 W ultrasonic power for 6 h, centrifuged at 3000 r/min for 10 minutes, and the supernatant was taken for comparison. The size and morphology of the six samples were observed by transmission electron microscopy. The absorbance of the quantum dot solution was measured by a UV-Vis-NIR absorption spectrometer, and the turbidity of the quantum dot solution was measured by a turbidity meter. The suitable exfoliation solvent for MoTe₂ quantum dots was determined using Hansen solubility theory.The results of transmission electron microscopy (Fig.2) show that the quantum dots prepared by 1-vinyl-2-pyrrolidone solution have the smallest size and the most uniform particle size. From the data of FTIR spectra and XRD patterns (Fig.3), it is known that the composition of quantum dots does not change during the ultrasonic process. The Hansen parameter diagram (Fig.6) shows that 1-vinyl-2-pyrrolidone with the smallest Ra value becomes a more suitable exfoliation solvent in theory. Combined with the statistical data and calculation results of (Tab.1) and (Tab.2), it is confirmed that 1-vinyl-2-pyrrolidone is indeed the suitable exfoliation solvent for MoTe₂.By comparing the liquid phase exfoliation effect of six kinds of solvents for MoTe₂, it was found that the choice of solvent directly affects the liquid phase exfoliation effect. Combined with the calculation results of Hansen solubility theory and the experimental results of turbidity method, it was concluded that 1-vinyl-2-pyrrolidone solvent was more suitable for liquid phase exfoliation of MoTe₂.