GH4169 samples were prepared by selective laser melting technique. The macroscopic and microscopic structure morphology and mechanical properties of the manufactured parts were analyzed by optical microscope, scanning electron microscope and electronic universal material testing machine. The results show that the crystal morphology of SLM molded parts is mainly cellular crystal, the diameter of fine columnar crystal is about 0.1～1.0 μm inside the "micro-melting pools", and the cross section is approximate hexagonal shape. Due to the different angles of laser incidence, powder uneven, temperature accumulation and change in heat dissipation conditions during the SLM process, the shape, length, width of the columnar crystal is different in the "micro-melting pools". The tensile specimens of SLM GH4169 molded parts present ductile fracture + cleavage fracture mode.