Response of greenhouse gas emissions in soil to climate change is a hot issue of agricultural response to climate change. The contents of nitrate and ammonium nitrogen, greenhouse gas emission flux, and emissions during the growing season in soil, combined with the yield of winter wheat were measured under elevated CO2 concentration (600 μmol/mol) and increased temperature (environment temperature+2℃). The global warming potential (GWP) and greenhouse gas emission intensity (GHGI) of winter wheat during the growing season were calculated. The results showed that the nitrate nitrogen content increased significantly at jointing stage under elevated CO2 concentration and increased temperature. The ammonium nitrogen content of winter wheat increased at the three stages under elevated CO2 concentration and increased temperature. Compared with T0C0, the total CO2 emissions during the growing season increased by 20.73%, 22.18% and 23.28% under T1C0, T0C1 and T1C1, respectively. The total emission of N2O during the growing season decreased by 26.35% and 18.41% under T0C1 and T1C0, respectively. Compared with T0C0, the total uptake of CH4 during the growing season significantly decreased by 93.56% under T0C1 and T1C1. Compared with T0C0, the yield of winter wheat under T1C0 significantly reduced by 19.93%, while it increased by 15.36% and 9.88% under T0C1 and T1C1, respectively. GWP significantly increased under T1C0, T0C1, and T1C1, while T1C0 significantly increased GHGI compared with T0C0. In conclusions, under elevated CO2 concentration and increased temperature in the future, total emissions of CO2 and N2O during growing season has increased to varying degrees. The total emissions of CH4 under increased temperature will be significantly reduced. GWP estimated by monitoring the three greenhouse gases emission in wheat fields under elevated CO2 concentration and increased temperature will provide theoretical support for the formulation of future agricultural emission reduction measures.