Printmaking is one of the typical folk arts, which has strong cultural deposits and personalized painting language. By analyzing the art form, subject matter, cultural connotation and other elements of printmaking, clothing designers explore the combination point of printmaking and clothing design, comprehensively consider the significance of printmaking's innovative presentation in clothing design, and then explore the presentation method and form of printmaking art in clothing design, so as to improve the compatibility between the two from the aspects of pattern, color and technique. It not only provides new ideas for the inheritance of printmaking, but also offers multiple materials for the innovation of clothing design.