A method for rapid determination of saccharin sodium in pastry and liquor was established by surface-enhanced Raman spectroscopy(SERS).Based on the solvent extraction method, dichloromethane was used to extract saccharin sodium from pastry and liquor.The concentrated gold colloid was prepared to use as Raman substrate, and the conditions of substrate was optimized.The results showed that saccharin sodium was extracted with dichloromethane under the acidic condition of 1 mol/L HCl, and saccharin sodium was back-extracted with 0.1 mol/L NaOH solution through adjusting the acidity of the system.When 1.0 mol/L HNO3 was used as coagulant to combine the concentrated gold colloid with saccharin sodium, the SERS signal with the strongest response could be obtained.The LOD of saccharin sodium in pastry and liquor were 0.5 mg/kg and 0.5mg/L respectively.And the recovery rate was between 75%~120% and RSD(n=5) was between 3.3~8.6%.So this method can be used for the rapid determination of saccharin sodium in pastry and liquor with the merit of high sensitivity, strong specificity and simple pretreatment method.