The finite element simulation software was used to establish the numerical model of laser removal of epoxy resin paint layer on the surface of AH32 steel, and loaded the pulsed laser on its surface for its cleaning process. The effects of different laser parameters on the temperature field of the laser removal of the paint layer on the surface of AH32 marine steel were investigated. The simulation results show that the maximum temperature of the paint layer surface changes with the movement of the spot center, and its scanning trajectory is comet-shaped;the maximum temperature of the paint layer surface decreases with the increase of the spot diameter and scanning speed, and increases with the increase of the laser repetition frequency and the laser power, and verify this law through the in-kind cleaning experiments, and observe the surface morphology of the cleaned surface, and get the results of the cleaning process when the laser power of 28 W, spot diameter of 0.05 mm, repetition frequency of 50 kHz and the scanning speed is 1 000 mm/s, not only can the paint layer be completely removed, but also the substrate material will not be damaged. The results of the study provide theoretical basis and experimental reference for laser cleaning of marine steel surface paint layer.