The axis consistency of multiple optical sensors is an important guarantee to ensure the normal operation for photoelectric task equipment of weapon system. The presented status quo of methods and equipment are ana-lyzed for measuring the consistency of large spacing axes. An axis consistency detection method is proposed based on non-cooperative target image processing technology. Specifically, it is available to select scenes with typical characteristics in the far field as non-cooperative targets. Then, the axis consistency detection results are obtained by comparing the position differences of non-cooperative targets in different image spaces. Compared with other detection methods and equipment, our method avoids many disadvantages including huge volume, heavy weight and the limited operation environment. Furthermore, it is especially suitable for axis detection of in field and on-line to large-distance photoelectric equipment, which shows a bright application prospect.