Compared with the common imaging, the polarization imaging contains more reflection and scattering information of the object surface. In this paper, polarization imaging method is used to obtain the degree of polarization image of skin surface under different light sources to study the effects of laser and LED light sources in the same waveband and laser and LED light sources in different wavebands on polarization imaging, in order to find a suitable type and waveband of polarization imaging lighting source for special disease. Results show that the information entropy and average gradient of laser polarization image are higher than those of LED polarization image under the same waveband light source. For the local imaging of erythema and mole on the skin, the image detail performance under green waveband illumination is better than that under red waveband illumination, providing more information for laser polarization imaging to improve the accuracy of skin state diagnosis.