It is demonstrated that femtosecond pulses transmit in microstructured fiber manufactured by our group. An 800 nm central wavelength of input pulses locates in the normal dispersion regime of the microstructured fiber. When the average power of initial input pulses increases from 220 mW to 300 mW, output spectrum spreads to long wavelength and short wavelength simultaneously, and the anti-Stokes emission in output spectrum holds on dominant status gradually. When the average power of input pulses increases to 280 mW, the scope of spectrum increases no longer. Output spectrum about 20 dB from 560 nm to 960 nm has been obtained by ultra-short pulses transmiting in a normal dispersion nonlinear manufactured fiber.