To improve the wear resistance property and bioactivity of Ti6Al4V alloy which is utilized as implant in medical application, the composite coating of Hydroxyapatite (HA)/TC4 is fabricated on the surface of Ti6Al4V alloy by laser cladding. This process has shown distinctive advantages due to combination the mechanical property of metal substrate and the biological property of ceramic coating. Through optimizing the ratio of HA/TC4 composite and laser cladding parameters, ideal single layer and multiple layer overlapped bioceramic composite coating is fabricated without metallic defects. The composite coating contains phases such as α -Ti, Ti3P, TiO, biocompatible ceramic phases as CaTiO3 and β -Ca3(PO4)2. The width of wear track of composite coating is lower than that of the substrate, which indicate that the wear resistance of Ti6Al4V alloy is significantly improved. The contact angle of simulated body fluid (SBF) against coating is smaller than that against the titanium substrate, which indicate that the wettability is improved by laser cladding coating.