Rh-B and Pyrromethene-597 laser dyes were successfully introduced into copolymer matrices of 2-hydroxypropyl methacrylate and methyl methacrylate. The spectral properties of two copolymer dye lasers were studied in the present paper. Pumped by a second harmonic Q-switched Nd:YAG laser (532 nm), laser oscillation was achieved in the well-polished φ25 mm×25 mm cylindrical Rh-B and PM-597 copolymers without resonance mirrors. It is found that in Rh-B doped copolymer, slope efficiency and center lasing wavelength was 35.3% and 590 nm, respectively. While in PM-597 doped copolymer, 62.2% slope efficiency and 585 nm center lasing wavelength were detected. The laser damage threshold was 62.5 MW/cm2 for Rhodamine-B doped laser and 200 MW/cm2 for Pyrromethene-597 doped laser.