This paper proposes a two-mirror telescope alignment method based on the on-axis field of view coma and off-axis symmetrical field of view astigmatism, utilizing vector aberration theory based on the aberration field characteristics of a misaligned Ritchey-Chrétien (R-C) telescope. A simulation alignment experiment is conducted on an R-C telescope, with random misalignments introduced into the secondary mirror. The alignment is successfully completed after three iterations using the proposed method, demonstrating its feasibility. An actual assembly experiment further validates the proposed method, achieving wave aberration values of 0.0730λ for the on-axis field of view and 0.0808λ and 0.0834λ for the two symmetrical off-axis fields of view, respectively. Experimental results indicate that the proposed method effectively aligns the R-C telescope, ensuring high imaging quality across all fields of view.