Object:To study the clinical effect of otorhinolaryngologicai papillomas treated by CO₂ laser. Methods:Among 166 cases were 45 cases of nasal papilloma, 39 cases of aural papilloma, and 82 cases of pharyngal papilloma. After local anaesthesia, We cut and vaporize tumor with CO2 laser in 15W of continuous output power. Results: The healing rate is near 100%. Conclusion:The methods have some advantages as follows: (1) With 70 - 90% of water in biologic tissues, laser hardly affect contiguous tissue during vaporizing tumor, and rarely affect healing of wound ; (2) After vaporizing and cutting tumor with laser, it can maximum keep the function of original organs, and not form tissue defection; (3) The laser can block and coagulate the vessel surrounding tumor tissue, so less bleeding during operating; (4) The laser incision is sterile, rarely affect infection of wound; (5) The operation is simple, so less painful for patient.