A novel method of fabricating zoom aspherical liquid micro-lens from ultra-violet (UV) curable polymer with on-line measurement is proposed. Electrostatic forces are employed to manipulate the shape of liquid polymer lens. Surface profile distortions of the liquid lens result in its focus variability. UV light is employed to cure the liquid lens when its surface profile and focal spot are appropriate. Therefore, aspherical micro-lens with nice optical imaging and focusing abilities can be fabricated. An experimental system which can fabricate zoom aspherical liquid micro-lenses and on-line measure their surface profiles and focal spots is developed. Experimental results show the variations of the surface profiles and focal spots of liquid lens changing with the electrostatic forces, and realize its zoom focus successfully. Fine aspherical surface profiles and focal spots of the liquid lens demonstrate the feasibility of fabricating aspherical micro-lens by using this method.