The concept of hybrid-pumped Tm-Ho co-doped pulse fiber laser by pumping the laser with a 1570 nm continuous-wave laser and a 1565 nm pulse laser is demostrated. The experimental setup is built up and stable pulse train of 2 μm is obtained. Directly gain-switched pulse train of Tm-Ho co-doped fiber laser is generated to compare the two methods of generating pulse laser. The results show that the hybrid-pumped pulse train is more stable than the gain-switched pulse train at the same laser output power level, and the energy fluctuation of the hybrid-pumped pulse train is less than 5%. Hence, the hybrid-pumped method is a more effective approach to generate stable pulse train. It should be noted that the pulse width of gain-switched pulse is narrower than that of the hybrid-pumped pulse.