Fluorescent nanodiamonds (FNDs) containing nitrogen vacancy (NV) centers exhibit broad prospects in quantum sensing, quantum computing, and fluorescence imaging due to their unique properties. Functionalizing FNDs with ordered porous metal-organic frameworks (MOFs) provides a controlled environment for quantum applications. This approach facilitates the immobilization of FNDs and enhances their interactions with other substances on their surface. This study explores a composite material of FNDs and MOFs. By encapsulating FNDs within the biocompatible metal organic framework zeolite imidazolate framework-8 (ZIF-8), the fluorescence and quantum sensing performance of FNDs were effectively preserved, and selective encapsulation by ZIF-8 resulted in observable changes in the fluorescence lifetime of FNDs. Furthermore, the study investigates the modulation effects of different synthesis conditions on the size and morphology of FNDs@ZIF-8. Through an in-depth exploration of FNDs@MOFs composite materials, the research unveils the quantum characteristics of FNDs within the composite, offering new avenues for designing more flexible, high-performance fluorescence imaging devices and quantum sensors.