MYB-CC gene family is transcription factor containing MYB-DNA binding domain and CC (coiled-coil) domain. The CC domain is a dimer domain that can participate in the interaction with proteins through structure folding. This is unique in plants that contain this domain of MYB-CC transcription factor. In addition to phosphate starvation response1 (PHR1), another 14 proteins in Arabidopsis thaliana also have these two domains. Some MYB-CC genes have shown to regulate phosphate uptake and control phosphate starvation in plants. In order to explore the characteristics and functions of MYB-CC gene family in foxtail millet, the characteristics and expression patterns of MYB-CC gene family in foxtail millet were analyzed by bioinformatics analysis. Finally, the collinearity and selection pressure of MYB-CC gene family in foxtail millet, rice and maize genomes were analyzed. The results showed that 18 genes of MYB-CC family were found on 7 chromosomes; a relatively conservative motif 1 was found in the motif analysis; cis-elements analysis showed that there were 6 MYB-CC genes involved in defense and stress response. The results of gene expression analysis showed that SiMYB-CC6 was specifically expressed in roots and stems. The results can provide reference for the further study of MYB-CC genes family in foxtail millet.