A pot experiment is conducted to investigate the effects of compound fertilizers with different sulfur chlorine ratios on the growth and development of potatoes. The experiment used pure sulfur based compound fertilizer treatment as the control (CK). The sulfur to chlorine ratios of the compound fertilizers in T1-T6 treatments are 1.5∶1, 2.5∶1, 3.5∶1, 4.5∶1, 5.5∶1, and 6.5∶1, respectively. The plant height, stem diameter, chlorophyll relative content (SPAD value), aboveground fresh weight, single potato weight, and quality of potatoes are measured. The results show that compared with CK treatment, when the sulfur chlorine ratio is greater than 2.5∶1, it has a promoting effect on potato plant height, stem thickness, SPAD value, aboveground fresh weight, single potato weight, and quality indicators. Under experimental conditions, T2 treatment has an ideal effect on promoting the growth and development of potatoes.