To mitigate the influence of temperature fluctuations on biological parameters, this paper proposes a multi-parameter sensing structure based on ring-core photonic crystal fiber (PCF) detection for measuring both the concentration of the breast cancer susceptibility gene (BRCA) and temperature. The proposed structure features an outer surface coated with a gold film, which creates a surface plasmon resonance sensing channel specifically designed for detecting BRCA concentration. Simultaneously, a thermosensitive liquid is filled into the central air holes of the PCF, forming a directional coupling sensing channel dedicated to precise temperature measurement. This design enables the correction of potential impacts of temperature changes on BRCA concentration measurements. The simulation results indicate that the concentration and temperature sensing channels of the sensor structure operate independently. Specifically, for the concentration sensing channel, when the BRCA concentration ranges from 0 to 7.69 mM, the concentration sensitivity can reach 19.5 nm/mM. For the temperature sensing channel, within a temperature range of 20 to 40℃, the temperature sensitivity is -6.4 nm/℃.