The medical laser has the advantages of small volume, high output power, light weight, good laser stability and easy to use. It has been used in medicine for more than 30 years. In recent 20 years, medical laser has become a powerful tool in urology surgery, more and more used in various fields of urology. With the progress of equipment and technology, medical laser has developed neodymium laser, green laser, holmium laser, thulium laser and other technologies. The characteristics of various laser devices and the new progress of clinical application of various laser technologies are reviewed.