Using water as coolant,experiments were used to study the spray cooling of 200 W/cm2 high power solid state laser for the heat dissipation. The heat transfer performance of spray cooling in the non-boiling regime was studied for volumetric flux ranged from 0.044 to 0.053 m3 /(m2·s) and the temperature ranged from 25-65 ℃. It was found that when the wall temperature was 65 ℃ and volumetric flux was 0.044 m3 /(m2·s),the heat flux dissipated could reach 257 W/cm2;when the volumetric flux increased to 0.053 m3 /(m2·s),the heat flux could reach 300 W/cm2 on the condition of the same surface temperature. Through analysis of experiments data,it was found that as the volumetric flux,wall temperature increasing,the heat transfer coefficient increased gradually. Further more,an empirical correlation between average Nusselt number Nu and the spray Reynolds number (Re>440) was developed. Compared with the data of Oliphant et al.,it was observed that the results from the correlation when Re is more than 240 could be of reference in the engineering application.