The high frequency acoustic lens focused ultrasonic transducer has important applications in electronic device evaluation and detection, material micro-mechanical properties characterization, biomedical imaging, cell manipulation, etc. The structural parameters are one of the main factors affecting its performance. In this paper, the high-frequency focused ultrasonic transducer based on acoustic lens structure is simulated by finite element method, and the influence of the opening angle of acoustic lens on the key performance parameters such as acoustic pressure pattern, lateral resolution and -6 dB depth of field in the focused region of this type of transducer is analyzed. The simulation results show that the focal length and lateral resolving power of the transducer are close to the theoretical calculation results. With the increase of the opening angle of the acoustic lens, the lateral resolving power of the transducer will be improved, the -6 dB depth of field will decrease, and the sound pressure level at the focus will increase. This paper provides a certain technical basis for the optimal design of acoustic lens focused ultrasonic transducer.