Based on the requirement of laser adjustment system for power supply output voltage accuracy and ripple, the paper proposed a circuit scheme for synchronous adjustment of positive and negative output voltage, designed a voltage regulator circuit controlled by a mirror current source and a power supply prototype for debugging. The power supply that was a simple structure, realized a high-precision voltage adjustment function with low ripple and met the requirement of laser adjustment system. The test result showed that the designed power supply achieved high-precision adjustable and low ripple output below 5 mV, met the requirements of laser trimming system for power supply.