Wavefront coding (WFC) is kind of computational imaging technique that controls misfocus and misfocus-related aberrations of optical systems by appending a specially designed phase distribution to the pupil function. This technology has been applied in many fields to increase the performance or/and reduce the cost of imaging systems. The application of WFC technology on an off-axis three-mirror anastigmatic (TMA) system has been proposed in our previous work. In this letter, we describe the alignment, the imaging experiment and image restoration of an actual TMA system with WFC technology.