we develop a novel coarse-to-fine method for the registration of the reference and target images,involving the 2D rigid transformation.The proposed method consists of four main steps:utilizing multi-scale Harris corner detector to extract the feature points in the reference and target images;corresponding these points by a novel feature points matching algorithm based on voting strategy,which efficiently eliminates the false and unstable matches;estimating transformation parameters with the matched feature points;refining the transformation parameters with the window-based method.Experimental results demonstrate that the proposed method is able to achieve high accuracy and robustness against noise with low computational burden.