Due to the measuring equipment and the influence of environment, there are some systematic errors in the data of high trajectory optical measurement. However, the systematic error correction is the key for high precision positional parameters. Aiming at this problem, the systematic error sources were analyzed when the target was above 80 km, the corresponding error model was set up, and the correction method was put forward according to the fixed star observation, based on the correction method of fixed star that the air refraction error and the axis errors of device were corrected together. To verify the effectiveness of the method, it was applied to the actual high trajectory optical measurement. The experimentation results show that the correction effect is obvious and the precision of correction can be improved to 2".