The match between the glass compositions and the overflow refractory is crucial for glass fusing draw processes. Static experiments and interface analysis were carried out to study the erosion influence of different components of lithium aluminosilicate glass on zircon overflow refractory. The experimental results show that the influence of sodium oxide content on the erosion of zircon overflow refractory is most significant. The higher the sodium oxide content, the lower the zircon breakdown temperature. As the same glass composition, the higher the temperature, the worse the erosion.