Research on laser-plasma interaction in China was conducted in parallel with the high power laser technique. Since 1964, the high power Nd:glass laser system has been developed, the laser breakdown and laser-focusing in the plasma were observed by focusing a 1.06 μm laser beam in the atmosphere. In 1973, frozen deuterrium and LiD,CD2 plate targets were irradiated by a 1010W laser beam, and a neutron yield of 1 x 103/shot was obtained. In 1974, with a 1011 W laser beam shotting on CD2 plate targets, th3 anomalous laser absorption and hard X-ray emission from plasma were observed, neutron yield of more than 2×104/shot was obtained. From 1975-1980, the compression of glass microballoon tergets was observed by using the six-beam laser facility. Moreover many laser-plasma interaction experiments, such as second harmonic emission, X-ray line spectrum diagnostics, K-edge absorption measurements for electron temperatures, Faraday cup charge collectors for particle measurements were carried out.