Binocular stereo vision system is equipped in laser remanufacturing robot. The robot can automatically find the defect of objects to be repaired and give the best repairing path and technological parameters. Calibration is the basic and key task of vision system. Two cameras are installed in the robot terminal and calibrate the two-dimentional (2D) plane target. The right and left cameras acquire target images in different positions by changing the camera′s positions through the robot teaching pendant. Internal and external camera parameters are calculated by OpenCV programming and robot hand-eye calibration is completed by Matlab. Calibration accuracy is analyzed with the help of robot teaching pendant. The result shows that the maximum relative error is 1.08%,which meets the requirements of laser-repairing remanufacturing.