Feasibility of rapid quantitative analysis for trace impurities in uranium materials is studied using laser induced breakdown spectroscopy (LIBS). LIBS system is set up with a KrF excimer laser and an AvaSpec-2048 fiber optic spectrometer. Spectral data both of uranium and impurity elements are detected and analyzed in a range of 200~460 nm wavelength. The influence of pulse number and delay time of spectrometer detection on the characteristics of uranium and impurity elements is investigated respectively. Three kinds of impurity elements Fe, Cu and Al in uranium are quantitatively analyzed with characteristic spectra at 438.3, 427.5, 396.2 nm respectively. The relative error of quantitative measurement is less than 12% when the laser energy is 28 mJ and time delay is 1.5 μs . The experimental results show that laser induced breakdown spectroscopy which has relatively lower relative error and limit of detection can be used for rapid quantitative analysis of trace impurity elements in uranium materials.